Autonomic Dysfunction in Parkinson's Disease: A Cross-Sectional Analysis of Cardiovagal and Adrenergic Functions and the Role of Dopaminergic Medications

Author : Yogesh Kumar

Abstract :Background: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, including significant autonomic dysfunction that profoundly affects patients' quality of life. Aim: This study aims to comprehensively evaluate cardiovagal and adrenergic functions in PD patients, analyze their relationship with disease severity, and assess the effects of dopaminergic medication on autonomic function. Methodology: A total of 60 PD patients and 30 healthy controls underwent autonomic function tests, including deep breathing, the Valsalva maneuver, and the head-up tilt test. For PD patients, assessments were conducted in both the ON and OFF medication states to determine the impact of dopaminergic therapy.

Keywords :Parkinson’s Disease, Autonomic Dysfunction, Cardiovagal Function, Adrenergic Function, Sudomotor Function, Heart Rate Variability, Baroreflex Sensitivity.

Conference Name :International Conference on Neurology Disorders, Stroke and Treatments (ICNDST-25)

Conference Place Las vegas, USA

Conference Date 29th Jan 2025