Paediatric Tc99m DMSA Renal Cortical Scintigraphy: Beyond Urinary Trac Infections

Author : Dr Kader Torbator, Lorenzo Biassoni, Riwa Meshaka

Abstract : Static renal cortical scintigraphy with 99mTc- dimercaptosuccinic acid ([99mTc] Tc-DMSA) is currently the imaging modality of choice to assess regional renal parenchymal function. The tracer uptake of 99mTc- reflects renal cortical integrity. DMSA is the test of choice for renal scarring following urinary tract infections. However, many other cortical defects can be detected, from acquired to congenital renal abnormalities1-3. This educational presentation will cover use of DMSA scanning in the following clinical contexts: • DMSA scanning in recurrent urinary tract infections and acute pyelonephritis • Functional characterization of structural renal abnormalities: e.g. solitary kidney, duplex kidney, small kidney, dysplastic kidney, horseshoe kidney, and pseudo-horseshoe kidney • Detection of renal ectopia – crossed fused kidney • Evaluation of renal parenchymal function in reno-vascular conditions – renovascular hypertension, renal vein thrombosis, renal septic embolism. • Assessment of renal parenchymal function in hydronephrosis • Evaluation of renal parenchymal damage post trauma • Renal parenchymal function assessment in complex renal calculi before and after treatment. • Assessment of function in multi-cystic dysplastic kidney

Keywords : DMSA scintigraphy, renal cortical function, renal scarring, pediatric nephrology, nuclear medicine

Conference Name : International Conference on Pediatric Radiology and Child Imaging (ICPRCI-26)

Conference Place : Istanbul, Turkey

Conference Date : 27th Jan 2026