Composite Materials with Immobilized AgNPs: A Sustainable Approach to Combat AMR

Author : Jana Soukupová

Abstract :Composite materials offer a promising route for advanced biomaterials, enabling tailored composition and surface properties. Silver nanoparticles (AgNPs) provide strong antimicrobial activity but raise toxicity concerns. Anchoring AgNPs onto solid, ideally polymer, pre-treated substrates via covalent bonding preserves their nanoscale size (≤50 nm) while improving safety and stability. We present a variety of composite materials, on the fundamental bases of substrate@AgNPs with high antimicrobial efficacy and controlled nanoparticle release, applicable in medical (implant protection, biofilm prevention) and environmental contexts (biofouling-resistant surfaces). This approach supports global efforts to combat antimicrobial resistance—a crisis responsible for 1.27 million deaths annually and projected to reach 10 million by 2050 (WHO). Acknowledgment: The work was supported by the project ‘Interdisciplinary Approaches to the Prevention and Diagnosis of Viral Diseases’ (CZ.02.01.01/00/23_021/0008856), funded by the European Regional Development Fund (ERDF) under the Jan Amos Komenský Operational Program and project no. TN02000051 funded by Technology Agency of the Czech Republic within the framework of the National Centres of Competence Program.

Keywords :Composite biomaterials, silver nanoparticles, antimicrobial surfaces, covalent anchoring, biofilm prevention

Conference Name :International Conference on Molecular Nanotechnology and Nanotechnology (ICMNNS - 25)

Conference Place Malaga,Spain

Conference Date 13th Dec 2025