Synthesis, characterisation of Cu(II) complex with water soluble analytical reagent like 2-[(5-hydroxy-3-methyl-1-(4-sulfophenyl)-1H-pyrazolyl)diazenyl]benzene-1,4-disulfonic acid and their biological activity

Author : Anil V. Patil, Ravindra L. Aavhare, Ketan C. Desai

Abstract :The metal complexes have been synthesized with the pyrazolone azo dye ligand 2-[(5-hydroxy-3-methyl-1-(4-sulfophenyl)-1H pyrazol-4-yl)diazenyl]benzene-1,4 disulfonic acid (HMSPDABDS) derived from aniline-2,5-disuphonic acid and 4-(5-hydroxy-3 methyl-1H-pyrazol-1-yl)benzene-1-sulfonic acid as a coupling compound by the diazotization reaction. The aniline-2, 5-disulphonic acid diazonium salt solution reacts in solution with pyrazolone coupler to form a coupling chemical. The metal complexes were made using Cu(II), Ni(II), Co(II), Mn(II), and Fe(III) with azo dye ligand. The various spectroscopic methods, including UV-visible, 1H NMR, and Fourier-transform infrared (FTIR), were used to identify and validate the synthesized ligand structures. Checking the melting point of the ligand allowed researchers to study its physical characteristics. The creation of metal complexes under ideal conditions has been investigated. The prepared metal ion complexes were recognized using UV-visible and FT-IR spectra, and their biological activities were also checked.

Keywords :Aromatic amines, Pyrazolone derivative, Metal complexes, Spectral studies, Heterocyclic acid dyes, Physico-chemical studies, Antibacterial activity.

Conference Name :International Conference on Research Challenges in Science and Technology (ICRCST-25)

Conference Place Panama City, Panama

Conference Date 7th May 2025